In Vitro Generation of Posterior Motor Neurons from Human Pluripotent Stem Cells

In Vitro Generation of Posterior Motor Neurons from Human Pluripotent Stem Cells

The ability to generate spinal cord motor neurons from human pluripotent stem cells (hPSCs) is of great use for modelling motor neuron–based diseases and cell-replacement therapies. A key step in the design of hPSC differentiation strategies aiming to produce motor neurons involves induction of the...

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Bibliographic Details
Main Authors: Tsakiridis, A. (Author), Wind, M. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
anterior posterior axis
Article
cell differentiation
Cell Differentiation
cell population
cell therapy
clinical protocol
controlled study
embryo development
Hox protein
human
human cell
human pluripotent stem cells (hPSCs)
Humans
in vitro study
motoneuron
motor neurons
Motor Neurons
nervous system development
Neurogenesis
neuromesodermal progenitors
pluripotent stem cell
Pluripotent Stem Cells
rhombencephalon
spinal cord
Spinal Cord
stem cell
thoracic spinal cord
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