Comprehensive analysis of the correlations of S100B with hypoxia response and immune infiltration in hepatocellular carcinoma

Comprehensive analysis of the correlations of S100B with hypoxia response and immune infiltration in hepatocellular carcinoma

S100B has been found to be dysregulated in many cancers including hepatocellular carcinoma (HCC). However, the functions of S100B and its underlying mechanisms in HCC remain poorly understood, especially in the tumor microenvironment. In this study, functions enrichment analysis indicated that S100B...

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Bibliographic Details
Main Authors: Huang, Q.Y (Author), Huang, Y.J (Author), Liu, P.X (Author), Wang, C.S (Author), Yan, J. (Author)
Format: Article
Language:English
Published: PeerJ Inc. 2022
Subjects:
Article
cell invasion
cell migration
chemokine receptor
chromatin immunoprecipitation
colony formation
correlation analysis
gene expression
gene knockdown
gene set variation analysis
genetic transcription
Hepatocellular carcinoma
Hep-G2 cell line
HIF-1a
human
human cell
hypoxia
Hypoxia
hypoxia inducible factor 1alpha
immune infiltration
Immune infiltration
immune response
immune-related gene
liver cell carcinoma
luciferase assay
MTT assay
natural killer cell
plasmid
protein protein interaction
protein S100B
real time polymerase chain reaction
S100B
transwell assay
tumor microenvironment
Western blotting
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