Evolution of Bacterial Persistence to Antibiotics during a 50,000-Generation Experiment in an Antibiotic-Free Environment

Failure of antibiotic therapies causes > 700,000 deaths yearly and involves both bacterial resistance and persistence. Persistence results in the relapse of infections by producing a tiny frac-tion of pathogen survivors that stay dormant during antibiotic exposure. From an evolutionary per-specti...

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Bibliographic Details
Main Authors: Amia, R. (Author), Gaffé, J. (Author), Martin, M. (Author), Mathé-Hubert, H. (Author), Schneider, D. (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher