Baicalein—A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury

Baicalein—A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury

Retinal ischemia is a common cause of many retinal diseases, leading to irreversible vision impairment and blindness. Excessive neuroinflammation, including microglial activation and T-cell responses, has been identified as a critical factor associated with neurodegeneration in retinal ischemia. Bai...

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Bibliographic Details
Main Authors: Chen, D.F (Author), Cho, K.-S (Author), Do, C.-W (Author), Lam, C. (Author), Pan, L. (Author), Sze, Y.H (Author), Tang, J. (Author), To, C.-H (Author), Yang, M. (Author), Yi, I. (Author), Zhao, S. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
adult
animal cell
animal experiment
animal model
animal tissue
antiinflammatory activity
Article
baicalein
cell infiltration
cervical lymph node
controlled study
electroretinography
enzyme phosphorylation
female
flow cytometry
IL-1β
immune response
immunofluorescence
immunoglobulin enhancer binding protein
immunohistochemistry
interleukin 17
interleukin 1beta
male
mass spectrometry
microglia
mouse
nerve degeneration
nervous system inflammation
neuroinflammation
neuroprotection
nonhuman
phosphatidylinositol 3 kinase
proteomics
real time polymerase chain reaction
retina ganglion cell
retina ischemia
retinal ischemia
Th17 cell
vision
Western blotting
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