Precision Vaccine Development: Cues From Natural Immunity

Precision Vaccine Development: Cues From Natural Immunity

Traditional vaccine development against infectious diseases has been guided by the overarching aim to generate efficacious vaccines normally indicated by an antibody and/or cellular response that correlates with protection. However, this approach has been shown to be only a partially effective measu...

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Bibliographic Details
Main Authors: Barman, S. (Author), Brook, B. (Author), Dowling, D.J (Author), Nanishi, E. (Author), Soni, D. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
adaptive immunity
adenylate cyclase toxin
adjuvants
antigens
Bordetella
Bordetella pertussis
CD4+ T lymphocyte
CD8+ T lymphocyte
clinical evaluation
cytokine
death
diphtheria
drug delivery system
drug formulation
fever
gamma interferon
hemagglutinin
hospitalization
human
immune response
immune system
immunopathology
infection
influenza
Influenza virus
innate immunity
interleukin 13
interleukin 17
interleukin 2
interleukin 21
interleukin 4
interleukin 5
lipooligosaccharide
lung edema
memory T lymphocyte
multiple organ failure
Mycobacterium bovis BCG
Mycobacterium tuberculosis
natural infection
nausea
nucleoprotein
pertussis
protein
regulatory T lymphocyte
Review
Tfh cell
Th1 cell
Th17 cell
Th2 cell
transcription factor FOXP3
tuberculosis
tumor necrosis factor
vaccine development
vaccines
virus vaccine
virus vector
vita-PAMP
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