Most Deleterious Missense Variants of Angiotensin-converting Enzyme 2 Gene have Extremely Low Frequencies and a Little Impact on the Binding Affinity with the SARS-CoV-2 Spike

Angiotensin-converting enzyme 2 (ACE2) is a well-established functional host receptor for the highly devastating ongoing pandemic of coronavirus disease 2019 (COVID-19). This protein provides the entry point through which COVID-19 hooks and infects human cells. A damaged ACE2 could alter the rate of...

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Bibliographic Details
Main Authors: Al-Shuhaib, J.M.B (Author), Al-Shuhaib, M.B.S (Author), Hashim, H.O (Author)
Format: Article
Language:English
Published: AMG Transcend Association 2023
Subjects:
SNP
Online Access:View Fulltext in Publisher