Most Deleterious Missense Variants of Angiotensin-converting Enzyme 2 Gene have Extremely Low Frequencies and a Little Impact on the Binding Affinity with the SARS-CoV-2 Spike
Angiotensin-converting enzyme 2 (ACE2) is a well-established functional host receptor for the highly devastating ongoing pandemic of coronavirus disease 2019 (COVID-19). This protein provides the entry point through which COVID-19 hooks and infects human cells. A damaged ACE2 could alter the rate of...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
AMG Transcend Association
2023
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Subjects: | |
Online Access: | View Fulltext in Publisher |