RhoA/ROCK signaling antagonizes bovine trophoblast stem cell self-renewal and regulates preimplantation embryo size and differentiation

RhoA/ROCK signaling antagonizes bovine trophoblast stem cell self-renewal and regulates preimplantation embryo size and differentiation

Exponential proliferation of trophoblast stem cells (TSC) is crucial in Ruminantia to maximize numerical access to caruncles, the restricted uterine sites that permit implantation. When translating systems biology of the undifferentiated bovine trophectoderm, we uncovered that inhibition of RhoA/Roc...

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Bibliographic Details
Main Authors:	Cheong, S.H (Author), Das, M. (Author), Gurung, S. (Author), Hansen, P.J (Author), Kei, T.G (Author), Pillai, V.V (Author), Selvaraj, V. (Author), Siqueira, L.G.B (Author)
Format:	Article
Language:	English
Published:	NLM (Medline) 2022
Subjects:	animal Animals blastocyst Blastocyst bovine Cattle cell differentiation Cell Differentiation Cell Self Renewal cell self-renewal female Female Implantation placenta Placenta pregnancy Pregnancy Stem cells trophoblast Trophoblast Trophoblasts
Online Access:	View Fulltext in Publisher

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