Cortical and Subcortical Dysmetabolism Are Dynamic Markers of Clinical Disability and Course in Anti-LGI1 Encephalitis

Cortical and Subcortical Dysmetabolism Are Dynamic Markers of Clinical Disability and Course in Anti-LGI1 Encephalitis

BACKGROUND AND OBJECTIVES: This [18F]fluorodeoxyglucose (FDG) PET study evaluates the accuracy of semiquantitative measurement of putaminal hypermetabolism in identifying anti-leucine-rich, glioma-inactivated-1 (LGI1) protein autoimmune encephalitis (AE). In addition, the extent of brain dysmetaboli...

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Main Authors: Bhattacharyya, S. (Author), Carter, K. (Author), Chitnis, T. (Author), Cicero, S. (Author), Ficke, J. (Author), Kijewski, J. (Author), Kijewski, M. (Author), Kim, C.K (Author), Klein, J.P (Author), Lyons, J. (Author), Park, M.-A (Author), Rissanen, E. (Author), Silbersweig, D. (Author), Singhal, T. (Author), Stern, E. (Author), Weiner, H.L (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
adolescent
Adolescent
adult
Adult
aged
Aged
Alzheimer disease
Alzheimer Disease
anti-leucine-rich glioma-inactivated 1 autoantibody
Autoantibodies
autoantibody
brain cortex
Cerebral Cortex
Demyelinating Autoimmune Diseases, CNS
demyelinating disease
diagnostic imaging
electroencephalography
Electroencephalography
encephalitis
Encephalitis
female
Female
follow up
Follow-Up Studies
human
Humans
immunology
Intracellular Signaling Peptides and Proteins
LGI1 protein, human
Magnetic Resonance Imaging
male
Male
mesencephalon
Mesencephalon
metabolism
middle aged
Middle Aged
nuclear magnetic resonance imaging
pathophysiology
positron emission tomography
Positron-Emission Tomography
putamen
Putamen
Retrospective Studies
retrospective study
signal peptide
young adult
Young Adult
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