Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse

Adaptive thermogenesis in small mammals and infants takes place in brown adipose tissue (BAT). Heat is produced via uncoupling protein 1 (UCP1)-mediated uncoupling between oxidation of energy substrates and adenosine 5'-triphosphate synthesis. Thyroid hormone (TH) signaling plays a role in this...

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Bibliographic Details
Main Authors: Bianco, A.C (Author), Fonseca, T.L (Author), Luongo, C. (Author), Russo, S.C (Author), Salvatore, D. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
D3
T3
Online Access:View Fulltext in Publisher