Molecular mechanism by which CDCP1 promotes proneural-mesenchymal transformation in primary glioblastoma

Molecular mechanism by which CDCP1 promotes proneural-mesenchymal transformation in primary glioblastoma

Background: Compared with the proneural (PN) subtype of glioblastoma (GBM), the mesenchymal (MES) subtype is more invasive and immune evasive and is closely related to poor prognosis. Here, we used transcriptome data and experimental evidence to indicate that CUB domain-containing protein 1 (CDCP1)...

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Bibliographic Details
Main Authors: Chen, C. (Author), Huang, G. (Author), Li, Z. (Author), Lin, Z. (Author), Liu, J. (Author), Wang, X. (Author), Wang, Y. (Author), Xu, H. (Author), Yi, G. (Author), Zhang, Z. (Author), Zheng, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
CDCP1
Epithelial-mesenchymal transition
Glioma
Prognostic risk model
Proneural-mesenchymal transition
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