Liraglutide preserves CD34+ stem cells from dysfunction Induced by high glucose exposure

Liraglutide preserves CD34+ stem cells from dysfunction Induced by high glucose exposure

Background: Glucagon like peptide-1 receptor agonists (GLP-1RAs) have shown to reduce mortality and cardiovascular events in patients with type 2 diabetes mellitus (T2DM). Since the impairment in number and function of vasculotrophic circulating CD34+ hematopoietic stem progenitor cells (HSPCs) in T...

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Main Authors: Arici, M. (Author), Barbuti, A. (Author), Fiorina, P. (Author), Gambini, E. (Author), Genovese, S. (Author), Metallo, A. (Author), Perrucci, G.L (Author), Pompilio, G. (Author), Raucci, A. (Author), Rinaldi, R. (Author), Rocchetti, M. (Author), Rurali, E. (Author), Sacco, E. (Author), Sforza, A. (Author), Vigorelli, V. (Author), Vinci, M.C (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Cardiovascular disease
CD34+ hematopoietic stem progenitor cells
GLP-1 receptor agonist
Type 2 diabetes mellitus
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