LINC00511 enhances LUAD malignancy by upregulating GCNT3 via miR-195-5p

LINC00511 enhances LUAD malignancy by upregulating GCNT3 via miR-195-5p

Background: Accumulating evidence suggests that LINC00511 acts as an oncogenic long non-coding RNA (lncRNA) in various cancers, including lung adenocarcinoma (LUAD). Hence, we attempted to elucidate the potential role of LINC00511 in LUAD. Methods: LINC00511, miR-195-5p, and GCNT3 expression in LUAD...

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Bibliographic Details
Main Authors: Hu, X. (Author), Xiao, P. (Author), Zhang, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
adenocarcinoma
Adenocarcinoma
bcl-2-Associated X Protein
Cell Line, Tumor
cell motion
Cell Movement
cell proliferation
Cell Proliferation
GCNT3
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
human
Humans
LINC00511
long untranslated RNA
LUAD
Lung Neoplasms
lung tumor
metabolism
microRNA
MicroRNAs
miR-195-5p
MIRN195 microRNA, human
pathology
protein Bax
RNA, Long Noncoding
tumor cell line
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