How I treat refractory/relapsed hairy cell leukemia with BRAF inhibitors

Hairy cell leukemia (HCL) responds very well to frontline chemotherapy with purine analogs (cladribine and pentostatine). However, approximately half of patients experience 1 or more relapses, which become progressively resistant to these myelotoxic and immunosuppressive agents. At progression, stan...

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Bibliographic Details
Main Authors: De Carolis, L. (Author), Falini, B. (Author), Tiacci, E. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Online Access:View Fulltext in Publisher