Retron reverse transcriptase termination and phage defense are dependent on host RNase H1
Retrons are bacterial retroelements that produce single-stranded, reverse-transcribed DNA (RT-DNA) that is a critical part of a newly discovered phage defense system. Short retron RT-DNAs are produced from larger, structured RNAs via a unique 2′-5′ initiation and a mechanism for precise termination...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2022
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Online Access: | View Fulltext in Publisher |