Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface

Unnatural base pairs (UBPs) which exhibit a selectivity against pairing with canonical nucleobases provide a powerful tool for the development of nucleic acid-based technologies. As an alternative strategy to the conventional UBP designs, which involve utility of different recognition modes at the W...

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Bibliographic Details
Main Authors: Dong, Z. (Author), Masaki, Y. (Author), Nagatsugi, F. (Author), Okamura, H. (Author), Seio, K. (Author), Trinh, G.H (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
Online Access:View Fulltext in Publisher