MAB21L4 regulates the TGF-β-induced expression of target genes in epidermal keratinocytes

MAB21L4 regulates the TGF-β-induced expression of target genes in epidermal keratinocytes

Smad proteins transduce signals downstream of transforming growth factor-β (TGF-β) and are one of the factors that regulate the expression of genes related to diseases affecting the skin. In the present study, we identified MAB21L4, also known as male abnormal 21 like 4 or C2orf54, as the most up-re...

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Bibliographic Details
Main Authors: Aburatani, H. (Author), Koinuma, D. (Author), Miyazawa, K. (Author), Miyazono, K. (Author), Morikawa, M. (Author), Ogami, T. (Author), Tamura, Y. (Author), Toss, K. (Author), Tsutsumi, S. (Author), Yuki, K. (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
Subjects:
ChIP-seq
c-Ski
Epidermal keratinocytes
genetics
human
Humans
keratinocyte
Keratinocytes
male
Male
metabolism
promoter region
Promoter Regions, Genetic
RNA, Small Interfering
signal transduction
Signal Transduction
Smad3
Smad3 protein
Smad3 Protein
small interfering RNA
TGF-β
transforming growth factor beta
Transforming Growth Factor beta
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