Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish

Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish

The process of sperm-egg fusion is critical for successful fertilization, yet the underlying mechanisms that regulate these steps have remained unclear in vertebrates. Here, we show that both mouse and zebrafish DCST1 and DCST2 are necessary in sperm to fertilize the egg, similar to their orthologs...

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Bibliographic Details
Main Authors: Berent, S. (Author), Blaha, A. (Author), Cabrera-Quio, L.E (Author), Deneke, V.E (Author), Emori, C. (Author), Fujihara, Y. (Author), Gert, K.R (Author), Ikawa, M. (Author), Kodani, M. (Author), Lu, Y. (Author), Noda, T. (Author), Oura, S. (Author), Panser, K. (Author), Pauli, A. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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