Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model

Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model

Brain derived neurotrophic factor (BDNF) promotes the growth, differentiation, maintenance and survival of neurons. These attributes make BDNF a potentially powerful therapeutic agent. However, its charge, instability in blood, and poor blood brain barrier (BBB) penetrability have impeded its develo...

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Bibliographic Details
Main Authors: Adam, C.W (Author), Kaufman, M.J (Author), Kim, J.K (Author), Lukas, S.E (Author), McLaughlin, J.P (Author), Shanmugavadivu, A. (Author), Subburaju, S. (Author), Vitaliano, F. (Author), Vitaliano, G.D (Author), Zeballos, G. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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