Translational Development of a Zr-89-Labeled Inhibitor of Prostate-specific Membrane Antigen for PET Imaging in Prostate Cancer

Translational Development of a Zr-89-Labeled Inhibitor of Prostate-specific Membrane Antigen for PET Imaging in Prostate Cancer

Purpose: We present here a Zr-89-labeled inhibitor of prostate-specific membrane antigen (PSMA) as a complement to the already established F-18- or Ga-68-ligands. Procedures: The precursor PSMA-DFO (ABX) was used for Zr-89-labeling. This is not an antibody, but a peptide analogue of the precursor fo...

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Bibliographic Details
Main Authors: Dietlein, F. (Author), Dietlein, M. (Author), Drzezga, A. (Author), Endepols, H. (Author), Fischer, T. (Author), Hohberg, M. (Author), Neumaier, B. (Author), Schomäcker, K. (Author), Tawadros, S.-G (Author), Vázquez, S.M (Author), Zimmermanns, B. (Author)
Format: Article
Language:English
Published: Springer Science and Business Media Deutschland GmbH 2022
Subjects:
Affinity
Biochemical recurrence
Biokinetics
Cell uptake
PET imaging
Prostate carcinoma
Radiochemistry
Zirconium-89
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