Chapter Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry
A characteristic of many proteoforms, derived from a single gene, is their similarity regarding the composition of atoms, making their analysis very challenging. Many overexpressed recombinant proteins are strongly associated with this problem, especially recombinant therapeutic glycoproteins from l...
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| Format: | eBook |
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InTechOpen
2019
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| Online Access: | Get fulltext |