A Multi-level Model for Analysing Whole Genome Sequencing Family Data with Longitudinal Traits
Compared to microarray-based genotyping, next-generation whole genome-sequencing (WGS) studies have the strength to provide greater information for the identification of rare variants, which likely account for a significant portion of missing heritability of common human diseases. In WGS, family-bas...
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Digital WPI
2013
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Online Access: | https://digitalcommons.wpi.edu/etd-theses/271 https://digitalcommons.wpi.edu/cgi/viewcontent.cgi?article=1270&context=etd-theses |