Engineering silk fibroin scaffolds to model hypoxia in neuroblastoma

Development of novel oncology therapeutics is limited by a lack of accurate pre-clinical models for testing, specifically the inability of traditional 2D culture to accurately mimic in vivo tumors. Neuroblastoma (NB) is a heterogeneous tumor, that in high-risk patients exhibits a 5-year event free s...

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Bibliographic Details
Main Author: Ornell, Kimberly J
Other Authors: Jeannine M. Coburn, Advisor
Format: Others
Published: Digital WPI 2019
Subjects:
Online Access:https://digitalcommons.wpi.edu/etd-dissertations/591
https://digitalcommons.wpi.edu/cgi/viewcontent.cgi?article=1591&context=etd-dissertations