The Role of IRF1 in the Brain and in Adaptive Responses of Astrocytes

In neurodegenerative diseases, the CNS becomes inflamed through activation of pathways, including the NF-B pathway. Some of the therapies for those diseases target neuroinflammatory pathways. Here, we explore the mechanisms for the upregulation of a subset of genes following a restimulation of the N...

Full description

Bibliographic Details
Main Author: Hoskins, Andrew
Format: Others
Published: VCU Scholars Compass 2019
Subjects:
EAE
Online Access:https://scholarscompass.vcu.edu/etd/5757
https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6868&context=etd