ALTERNATIVE SPLICING OF CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN 2 IS MODULATED VIA SERINE ARGININE SPLICING FACTOR 3 IN CANCER METASTASIS

ALTERNATIVE SPLICING OF CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN 2 IS MODULATED VIA SERINE ARGININE SPLICING FACTOR 3 IN CANCER METASTASIS

Our laboratory delineated a role for alternative pre-mRNA splicing (AS) in triple negative breast cancer (TNBC). We found the translational regulator cytosolic polyadenylation element binding protein 2 (CPEB2) which has two isoforms, CPEB2A and CPEB2B, is alternatively spliced during acquisition of...

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Bibliographic Details
Main Authors: DeLigio, James T, DeLigio, James Thomas
Format: Others
Published: VCU Scholars Compass 2018
Subjects:
alternative pre-mRNA splicing
gene regulation
transcriptional control of cell differentiation
tumor progression
invasion and metastasis
cell motility and migration
breast cancer
Cancer Biology
Medical Biochemistry
Medical Molecular Biology
Molecular Genetics
Online Access:https://scholarscompass.vcu.edu/etd/5660
https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6735&context=etd

Internet

https://scholarscompass.vcu.edu/etd/5660
https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6735&context=etd

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