The interaction between ceramide-1-phosphate and Group IVA cytosolic phospholipase A2 and its role in wound healing
The sphingolipid, ceramide-1-phosphate (C1P), directly binds and activates Group IVA cytosolic phospholipase A2 (cPLA2a) to generate eicosanoids. Due to the role of eicosanoids in wound healing, we choose to use our novel genetic mouse model expressing cPLA2a with an ablated C1P interaction site (KI...
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| Format: | Others |
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VCU Scholars Compass
2018
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| Online Access: | https://scholarscompass.vcu.edu/etd/5633 https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6717&context=etd |