Orientia tsutsugamushi Modulates Endoplasmic Reticulum Stress to Benefit its Intracellular Growth and Targets NLRC5 to Inhibit Major Histocompatibility Complex I Expression
Scrub typhus, caused by the obligate intracellular bacterium Orientia tsutsugamushi, afflicts one million people annually. Despite being a global health threat, little is known about O. tsutsugamushi pathogenesis. Here, we demonstrate that O. tsutsugamushi modulates the ER and ER-associated processe...
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VCU Scholars Compass
2018
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| Online Access: | https://scholarscompass.vcu.edu/etd/5264 https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6340&context=etd |