MAST CELL ACTIVATION BY DIVERSE STIMULI CAN BE SUPPRESSED BY STEROID THERAPY AND TARGETING THE FYN-STAT5B CASCADE

Mast cells are critical effectors of allergic disease that can be activated by numerous stimuli. We have examined mast cell control by the inflammatory cytokine, IL-33, as well as IgG. In the first study reported here, we found that the synthetic glucocorticoid, dexamethasone, potently and rapidly s...

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Bibliographic Details
Main Author: Paranjape, Anuya
Format: Others
Published: VCU Scholars Compass 2017
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/5069
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6149&context=etd