CONTRIBUTION OF A CLASS II RIBONUCLEOTIDE REDUCTASE TO THE MANGANESE DEPENDENCE OF Streptococcus sanguinis

Manganese-deficient Streptococcus sanguinis mutants exhibit a dramatic decrease in virulence for infective endocarditis and in aerobic growth in manganese-limited media. Loss of activity of a manganese-dependent, oxygen-dependent ribonucleotide reductase (RNR) could explain the decrease in virulence...

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Bibliographic Details
Main Author: Smith, John L
Format: Others
Published: VCU Scholars Compass 2017
Subjects:
Fba
Online Access:http://scholarscompass.vcu.edu/etd/4936
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6015&context=etd