ATM phosphorylates subunit A of PP2A resulting in its nuclear export and spatiotemporal regulation of the DNA damage response
Ataxia telangiectasia mutated (ATM) is a serine-threonine protein kinase and major regulator of the DNA damage response (DDR). One critical ATM target is protein phosphatase 2A (PP2A) known to regulate diverse cellular processes such as mitosis and cell growth as well as dephosphorylation of many pr...
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| Format: | Others |
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VCU Scholars Compass
2016
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| Online Access: | http://scholarscompass.vcu.edu/etd/4677 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5692&context=etd |