The role of ADAM10, ADAM17, and Spag6 in humoral immunity and secondary lymphoid tissue architecture

ADAM10, ADAM17, and SPAG6 contribute significantly to humoral immunity and secondary lymphoid tissue architecture. ADAM10 and ADAM17 are two closely related zinc-metalloproteinases. Through cleavage of their ligands CD23 and TNF, respectively, they greatly influence IgE production and secondary lymp...

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Bibliographic Details
Main Author: Cooley, Lauren Folgosa
Format: Others
Published: VCU Scholars Compass 2015
Subjects:
B10
IgE
Online Access:http://scholarscompass.vcu.edu/etd/3808
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4718&context=etd