Enhanced Epithelial-to-Mesenchymal Transition Associated with Lysosome Dysfunction in Podocytes: Role of p62/Sequestosome 1 as a Signaling Hub
Autophagy is of importance in the regulation of cell differentiation and senescence in podocytes, the highly differentiated glomerular epithelial cells. It is possible that derangement of autophagy under different pathological conditions activates or enhances Epithelial-to-Mesenchymal Transition (EM...
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VCU Scholars Compass
2015
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| Online Access: | http://scholarscompass.vcu.edu/etd/3698 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4713&context=etd |