Quantitative Genetic Methods to Dissect Heterogeneity in Complex Traits

Etiological models of complex disease are elusive[46, 33, 9], as are consistently replicable findings for major genetic susceptibility loci[54, 14, 15, 24]. Commonly-cited explanations invoke low-frequency genomic variation[41], allelic heterogeneity at susceptibility loci[33, 30], variable etiologi...

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Bibliographic Details
Main Author: Bigdeli, T. Bernard
Format: Others
Published: VCU Scholars Compass 2012
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/2651
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3650&context=etd

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