Quantitative Genetic Methods to Dissect Heterogeneity in Complex Traits
Etiological models of complex disease are elusive[46, 33, 9], as are consistently replicable findings for major genetic susceptibility loci[54, 14, 15, 24]. Commonly-cited explanations invoke low-frequency genomic variation[41], allelic heterogeneity at susceptibility loci[33, 30], variable etiologi...
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VCU Scholars Compass
2012
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Online Access: | http://scholarscompass.vcu.edu/etd/2651 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3650&context=etd |