Inhibition of cytomegalovirus genome maturation by the halogenated benzimidazoles
Current FDA approved anti-cytomegalovirus antivirals are ganciclovir, foscarnet, and cidofovir. These drugs target the viral polymerase to inhibit DNA synthesis. Halogenated benzimidazoles target a step later in viral replication during packaging and cleavage of the viral genome. The compounds 2-Bro...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
VCU Scholars Compass
2010
|
| Subjects: | |
| Online Access: | http://scholarscompass.vcu.edu/etd/2453 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3452&context=etd |