Nucleoplasmic and Cytoplasmic Degradation of Telomerase: implications toward telomerase-based cancer therapy
Telomerase is a ribonucleoprotein that is reactivated in cancer cells to allow for continuous cellular division and indefinite growth. With telomerase being expressed in more than 85% of all cancer, it is imperative that we understand how to selectively inactivate and degrade this unique DNA polymer...
Main Author: | Nguyen, Binh |
---|---|
Format: | Others |
Published: |
VCU Scholars Compass
2008
|
Subjects: | |
Online Access: | http://scholarscompass.vcu.edu/etd/1933 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2932&context=etd |
Similar Items
-
An Alternate Splicing Variant of the Human Telomerase Catalytic Subunit Inhibits Telomerase Activity
by: Xiaoming Yi, et al.
Published: (2000-09-01) -
The hTERTα Splice Variant is a Dominant Negative Inhibitor of Telomerase Activity
by: Lorel M. Colgin, et al.
Published: (2000-09-01) -
TELOMERASE REVERSE TRANSCRIPTASE IN ATHEROSCLEROSIS
by: Qing, Hua
Published: (2017) -
Telomerase Inhibition and Sensitization of Breast Tumor Cells
by: Poynter, Kennon R.
Published: (2007) -
Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies
by: Lindsey B. Shelton, et al.
Published: (2017-12-01)