Nucleoplasmic and Cytoplasmic Degradation of Telomerase: implications toward telomerase-based cancer therapy

Telomerase is a ribonucleoprotein that is reactivated in cancer cells to allow for continuous cellular division and indefinite growth. With telomerase being expressed in more than 85% of all cancer, it is imperative that we understand how to selectively inactivate and degrade this unique DNA polymer...

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Bibliographic Details
Main Author: Nguyen, Binh
Format: Others
Published: VCU Scholars Compass 2008
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/1933
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2932&context=etd