Nucleoplasmic and Cytoplasmic Degradation of Telomerase: implications toward telomerase-based cancer therapy
Telomerase is a ribonucleoprotein that is reactivated in cancer cells to allow for continuous cellular division and indefinite growth. With telomerase being expressed in more than 85% of all cancer, it is imperative that we understand how to selectively inactivate and degrade this unique DNA polymer...
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VCU Scholars Compass
2008
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Online Access: | http://scholarscompass.vcu.edu/etd/1933 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2932&context=etd |