FACTORS INFLUENCING PLACENTAL TRANSFER OF LOPINAVIR: BINDING, UPTAKE AND EFFLUX
HIV protease inhibitors are an important component of Highly Active Antiretroviral Therapy used to treat HIV infected pregnant women. They have a low placental transfer and are highly plasma protein bound. The purpose of this thesis was to characterize the factors limiting placental passage and feta...
Main Author: | Gulati, Abhishek |
---|---|
Format: | Others |
Published: |
VCU Scholars Compass
2009
|
Subjects: | |
Online Access: | http://scholarscompass.vcu.edu/etd/1852 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2851&context=etd |
Similar Items
-
The Role of PXR Genotype and Transporter Expression in the Placental Transport of Lopinavir in Mice
by: Sarabjit S. Gahir, et al.
Published: (2017-10-01) -
Small Molecules Binding to Serpins
by: Afridi, Junaid
Published: (2006) -
STUDY OF MOLECULAR INTERACTIONS OF GLYCOSAMINOGLYCANS AND GLYCOSAMINOGLYCAN MIMETICS WITH THEIR PROTEIN TARGETS
by: Afosah, Daniel K
Published: (2017) -
Enhancement of the Placental Transmission of Lopinavir Using a Transporter Targeted Prodrug Strategy
by: Wang, Meng
Published: (2015) -
IN-VITRO METABOLISM AND PROTEIN BINDING OF 5-HMF, A POTENTIAL ANTISICKLING AGENT
by: Obied, Taghrid
Published: (2010)