FACTORS INFLUENCING PLACENTAL TRANSFER OF LOPINAVIR: BINDING, UPTAKE AND EFFLUX

HIV protease inhibitors are an important component of Highly Active Antiretroviral Therapy used to treat HIV infected pregnant women. They have a low placental transfer and are highly plasma protein bound. The purpose of this thesis was to characterize the factors limiting placental passage and feta...

Full description

Bibliographic Details
Main Author: Gulati, Abhishek
Format: Others
Published: VCU Scholars Compass 2009
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/1852
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2851&context=etd