Novel Sulfated 4-Hydroxycinnamic Acid Oligomers as Potent Anticoagulants

The occurrence of thrombosis in several pathophysiological conditions creates a huge need for anticoagulation therapy. Thrombin and factor Xa have been prime targets for regulation of clotting through the direct and indirect mechanism of inhibition. This work investigates chemo-enzymatically prepar...

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Bibliographic Details
Main Author: Henry, Brian Lawrence
Format: Others
Published: VCU Scholars Compass 2007
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/1462
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2461&context=etd