EFFECTS OF MU OPIOID RECEPTOR AGONISTS ON INTRACRANIAL SELF-STIMULATION IN THE ABSENCE AND PRESENCE OF “PAIN” IN RATS

EFFECTS OF MU OPIOID RECEPTOR AGONISTS ON INTRACRANIAL SELF-STIMULATION IN THE ABSENCE AND PRESENCE OF “PAIN” IN RATS

Pain is a significant health problem. Mu opioid receptor agonists are used clinically as analgesics, but their use is constrained by high abuse liability. Intracranial self-stimulation (ICSS) is a preclinical behavioral procedure that has been used to assess abuse potential of opioids, and drug-ind...

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Bibliographic Details
Main Author: Altarifi, Ahmad
Format: Others
Published: VCU Scholars Compass 2013
Subjects:
opioids
intracranial self-stimulation
pain
opioid efficacy
opioid abuse
opioid dependence
mu receptor
chronic morphine
rats
Medical Pharmacology
Medical Sciences
Medicine and Health Sciences
Online Access:http://scholarscompass.vcu.edu/etd/518
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1517&context=etd

Internet

http://scholarscompass.vcu.edu/etd/518
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1517&context=etd

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