DEVELOPMENT OF ANTAGONISTS TARGETING CHEMOKINE RECEPTOR CCR5 AND THE CHEMOKINE RECEPTOR CCR5 – MU OPIOID RECEPTOR HETERODIMER

DEVELOPMENT OF ANTAGONISTS TARGETING CHEMOKINE RECEPTOR CCR5 AND THE CHEMOKINE RECEPTOR CCR5 – MU OPIOID RECEPTOR HETERODIMER

The chemokine receptor CCR5 (CCR5) plays an integral role within the inflammatory network of cells. Importantly, CCR5 is a mediator in several disease states and can be targeted using small molecule antagonists. Within this work, CCR5’s role in prostate cancer and HIV/AIDS has been exploited in orde...

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Bibliographic Details
Main Author: Arnatt, Christopher Kent
Format: Others
Published: VCU Scholars Compass 2013
Subjects:
Bivalent
Opioid
CCR5
AIDS
HIV
Prostate cancer
neuroAIDS
Medicine and Health Sciences
Pharmacy and Pharmaceutical Sciences
Online Access:http://scholarscompass.vcu.edu/etd/517
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1516&context=etd

Internet

http://scholarscompass.vcu.edu/etd/517
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1516&context=etd

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