NONCOVALENT INTERACTION OF PLATINUM PLANAR AMINE COMPOUNDS WITH TRYPTOPHAN: A STRATEGY TO INTERFERE WITH P53-MDM2 INTERACTIONS AND TARGETING RETROVIRAL ZN FINGER-DNA INTERACTION (HIV NCP7)
Non-covalent interactions involving π-π stacking play an essential role in self-assembly and molecular recognition processes such as protein folding and DNA/RNA-protein selective recognition. The knowledge gained from these studies could provide insight into possible site recognition complexes, inhi...
Main Author: | |
---|---|
Format: | Others |
Published: |
VCU Scholars Compass
2009
|
Subjects: | |
Online Access: | http://scholarscompass.vcu.edu/etd/29 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1028&context=etd |