Influences of ageing and diet on mutational frequency and specificity in Big Blue® lacI transgenic rodents
Big Blue® lacI transgenic mice and rats carry the E. coli lacI gene integrated as a tandem array of approximately 40 copies integrated at a single site in chromosome 4. This mutationally well-characterized gene is highly sensitive to base substitution mutations and is readily recovered from virtuall...
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| Format: | Others |
| Language: | English en |
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2018
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| Online Access: | https://dspace.library.uvic.ca//handle/1828/8991 |