Synthetic investigation of small-molecule probes
A series of small molecules was synthesized to probe three protein targets in order to elucidate the key small molecule-protein interactions required for potency. Triclosan is an antibacterial compound that has surfaced as a potential environmental hazard and is hypothesized to cause perturbations i...
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Language: | English en |
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2012
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Online Access: | http://hdl.handle.net/1828/4354 |