Characterization of spermatogenic histone variants with special emphasis on histone H2A.X and double stranded break repair
The fundamental subunit of chromatin, known as a nucleosome, is comprised of DNA wrapped around two H2A-H2B dimers and one H3-H4 tetramer. This structure perpetuates itself and together with linker histones (histone H1) give rise to the chromatin fibre. This causes compaction of DNA within the nucle...
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Language: | English en |
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2010
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Online Access: | http://hdl.handle.net/1828/2681 |