Expression of glucocerebrosidase in humanized Pichia pastoris expression system and protein purification
Gaucher Disease (GD) is characterized by the accumulation of glucocerebroside, leading to enlargement of the liver and spleen and lesions in bones. It is caused by an inherited deficiency of the enzyme glucocerebrosidase (GBA). GD results in chronic pain, fatigue, jaundice. bone damage, anemia, hepa...
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| Language: | English en |
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2010
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| Online Access: | http://hdl.handle.net/1828/2403 |