The expression of α-N-acetylglucosaminidase in the methylotrophic yeast Pichia pastoris

The expression of α-N-acetylglucosaminidase in the methylotrophic yeast Pichia pastoris

Mucopolysaccharidosis IIIB (MPS IIIB) is an autosomal recessive disorder of glycosaminoglycan (GAG) metabolism. Disruption of the gene encoding a-N-acetylglucosaminidase (Naglu) results in the inability to degrade the GAG heparan sulfate (HS). Consequently. undegraded HS builds up and results in the...

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Bibliographic Details
Main Author: Patrick, Chelsea Marie
Other Authors: Choy, Francis
Language:English
en
Published: 2009
Subjects:
mucopolysaccharidosis
pichia pastoris
glycosaminoglycan
UVic Subject Index::Sciences and Engineering::Biology
Online Access:http://hdl.handle.net/1828/1869

Internet

http://hdl.handle.net/1828/1869

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