Structural and biochemical investigation of the regulation of Rab11a by the guanine nucleotide exchange factors SH3BP5 and TRAPPII

Rab11 is a critical GTPase involved in the regulation of membrane trafficking in the endocytic pathway, and it’s misregulation is involved in a variety of human diseases including Huntington’s disease and Alzheimer’s disease. Additionally, de novo mutations (DNMs) of Rab11 have been identified in pa...

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Bibliographic Details
Main Author: Jenkins, Meredith L.
Other Authors: Burke, John E
Format: Others
Language:English
en
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/1828/11343

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