Structural and biochemical investigation of the regulation of Rab11a by the guanine nucleotide exchange factors SH3BP5 and TRAPPII
Rab11 is a critical GTPase involved in the regulation of membrane trafficking in the endocytic pathway, and it’s misregulation is involved in a variety of human diseases including Huntington’s disease and Alzheimer’s disease. Additionally, de novo mutations (DNMs) of Rab11 have been identified in pa...
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| Format: | Others |
| Language: | English en |
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2019
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| Online Access: | http://hdl.handle.net/1828/11343 |