Structural analysis of DNA wrapping in bacterial transcription initiation complex by transmission electron microscopy and single particle analysis

The transcription initiation is the first step in gene expression and an important regulation step in all living organisms. In bacteria, it has been proposed that DNA bending and its wrapping on the surface of E. coli RNAP might facilitate the opening of the transcription bubble, which is necessary...

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Bibliographic Details
Main Author: Ariza, Alfredo Jose Florez
Other Authors: Portugal, Rodrigo Villares
Format: Others
Language:en
Published: Biblioteca Digitais de Teses e Dissertações da USP 2018
Subjects:
Online Access:http://www.teses.usp.br/teses/disponiveis/76/76132/tde-19102018-090529/